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We investigate whether the diseases for which there was more biomedical innovation had larger 1999–2019 reductions in premature mortality. Biomedical innovation related to a disease is measured by the change in the mean vintage of descriptors of PubMed articles about the disease. We analyze data on 286 million descriptors of 27 million articles about over 800 diseases. Premature mortality from a disease is significantly inversely related to the lagged vintage of descriptors of articles about the disease. In the absence of biomedical innovation, age-adjusted mortality rates would not have declined. Some factors other than biomedical innovation (e.g., a decline in smoking and an increase in educational attainment) contributed to the decline in mortality. But other factors (e.g., a rise in obesity and the prevalence of chronic conditions) contributed to an increase in mortality. Biomedical innovation reduced the mortality of white people sooner than it reduced the mortality of black people.
In the first book-length history of the Board of Longitude, a distinguished team of historians of science bring to life one of Georgian Britain's most important scientific institutions. Having developed in the eighteenth century following legislation offering rewards for methods to determine longitude at sea, the Board came to support the work of navigators, instrument makers, clockmakers and surveyors, and assembled the Nautical Almanac. Utilizing the archives and records of the Board, recently digitised by the same team, the authors shed new light on the Board's involvement in colonial projects, Pacific and Arctic exploration, as well as on innovative practitioners whose work would otherwise be lost to history. This is an invaluable guide to science, state and society in Georgian Britain, a period of dramatic industrial and imperial and technological expansion.
Drawing inspiration from Oliver Williamson’s work, we employ a ‘discriminating alignment’ approach to explain how established organizations select and govern external sources of innovation. Our framework integrates ‘standard’ governance mechanisms, such as licensing and joint ventures, with ‘emerging’ mechanisms, such as hackathons and accelerators. First, we classify governance mechanisms into three types – market scanning, opportunity support, and opportunity control – based on four attributes: the degree of reallocation of decision rights, the degree of pooling of property rights, set-up costs, and ex post adaptation costs. We then argue that two key variables – uncertainty and technological distance – jointly help determine the choice of the appropriate mechanism for transactions involving entrepreneurial opportunities. By developing a comprehensive taxonomy of arrangements linked to the governance of external innovations, this study offers propositions that identify the drivers of ‘efficient alignment’ between transactions attributes and organizational choices in entrepreneurial contexts.
Chapter 14 presents a dynamic model of long-term, art historical trends and shows the complexity of overlapping styles and movements. It is based on a modification af a dynamic model of development on the timescale of the human life course. The basic evolution rules are those of simultaneously operating processes of consolidation of the status quo and processes of innovation driven by a familiarity-novelty optimum. The simulation explores different scenarios, one of which generates the typical art-historical pattern of overlapping continuous as well as discontinuous processes.
Despite enormous efforts at healthcare improvement, major challenges remain in achieving optimal outcomes, safety, cost, and value. This Element introduces the concept of learning health systems, which have been proposed as a possible solution. Though many different variants of the concept exist, they share a learning cycle of capturing data from practice, turning it into knowledge, and putting knowledge back into practice. How learning systems are implemented is highly variable. This Element emphasises that they are sociotechnical systems and offers a structured framework to consider their design and operation. It offers a critique of the learning health system approach, recognising that more has been said about the aspiration than perhaps has been delivered. This title is also available as open access on Cambridge Core.
There are myriad open questions and challenges for the Unified Patent Court (UPC) system and the unitary patent, which constitute a new layer to the European patent landscape on top of the existing courts and types of patents. One of those is the question of how this new system will interact with utility models, which seems to have mostly escaped academic scrutiny so far. This chapter explores this interaction, focusing predominantly on the consequences of the new unitary patent and the UPC for strategies surrounding patents and utility models, including the division of judicial competence. By considering, amongst other things, the complicated relationship and overlap of these rights, the limited but influential mandate of the UPC, the fragmented landscape for utility models, and the different sources of law governing a unitary patent, this chapter examines how litigation before the UPC may affect (strategies involving) utility models.
Since 1985, when China’s first Patent Law came into effect, China has established a legal protection system for utility models. At present, after four revisions of the Patent Law, China’s utility model patent legal system has also been improved. However, among the authorized utility model patents, those that fully meet the necessary conditions of novelty and inventive step might be in the minority. Of course, this phenomenon is not unique in China. The purpose of this chapter is to illuminate the ongoing optimization of the Chinese utility model patent system in the context of the development of China’s overall patent system. Accordingly, Part Ⅰ traces the emergence of China’s Patent System, including the Chinese utility model patent-based subsystem. Part Ⅱ centers on the basic contours of the Chinese utility model patent system. Part Ⅲ then summarizes existing deficiencies of the Chinese utility model patent system and future development trends. It concludes with a discussion of potential implications of proposed revisions to the Chinese utility model patent system.
In Germany, the utility model is a type of intellectual property right that provides protection for novel and useful inventions. It is governed by the German Utility Model Act (“Gebrauchsmustergesetz” – GebrMG) which was enacted in 1891, making it the oldest still-existing utility model system in the world. Utility models grant the right holder exclusive control over the use and commercialisation of an invention for a period of ten years from the date of filing, subject to the payment of annual renewal fees. In a way, the utility model is the “little sister” of a full-fledged patent (also called a “petty patent”), protecting the same type of subject matter (technical inventions) with a more limited scope.
While national rules regarding the scope, availability and issuance of utility models vary from country to country, most utility model regimes offer protection for tangible products, with many, but not all, jurisdictions excluding processes, biological materials and computer software from the scope of protection. The duration of utility model protection ranges from five to fifteen years, with most countries offering ten years of protection. In most countries, utility model applications are not formally examined and must simply disclose the product in question. Given the lack of examination, obtaining utility models is generally viewed as faster and cheaper than obtaining patents. This combination of speed and cost, in theory, makes utility models potentially attractive to small and medium enterprises (SMEs) that cannot afford to obtain full patent protection. Similar considerations have also been raised as advantageous to innovators in low-income countries.
In virtually all societal domains, algorithmic systems, and AI more particularly, have made a grand entrance. Their growing impact renders it increasingly important to understand and assess the challenges and opportunities they raise – an endeavor to which this book aims to contribute. In this chapter, I start by putting the current “AI hype” into context. I emphasize the long history of human fascination with artificial beings; the fact that AI is but one of many powerful technologies that humanity has grappled with over time; and the fact that its uptake is inherently enabled by our societal condition. Subsequently, I introduce the chapters of this book, dealing with AI, ethics and philosophy (Part I); AI, law and policy (Part II); and AI across sectors (Part III). Finally, I discuss some conundrums faced by all scholars in this field, concerning the relationship between law, ethics and policy and their roles in AI governance; the juxtaposition between protection and innovation; and law’s (in)ability to regulate a continuously evolving technology. While their solutions are far from simple, I conclude there is great value in acknowledging the complexity of what is at stake and the need for more nuance in the AI governance debate.
This conversation centres around innovation in the financial services sector and the related regulatory supervision. Three ‘Techs’ are especially relevant: FinTech, RegTech and SupTech. ‘FinTech’ combines the words ‘financial’ and ‘technology’ and refers to technological innovation in the delivery of financial services and products. ‘RegTech’ joins ‘regulatory’ and ‘technology’ and describes the use of technology by businesses to manage and comply with regulatory requirements. ‘SupTech’, finally, unites the words ‘supervisory’ and ‘technology’ to refer to the use of technology by supervisory authorities such as financial services authorities to perform their functions. Particular approaches presented in this session include regulatory sandboxes to promote innovative technology in the financial sector, automated data analysis, the collection and analysis of granular data, digital forensics and internet monitoring systems. The speakers also address collaboration between financial institutions and supervisory authorities, for example, in the creation of data collection formats and data sharing.
Unlike most of the other jurisdictions discussed in this book, the United States (US) does not currently have, nor did it ever have, a utility model or other system of second-tier patent protection. This being said, discussion and debate over the institution of such a system in the US has been ongoing for more than a century. In this chapter, we discuss the history and current status of this debate, as well as alternative approaches that US agencies and legislators have taken to address the needs and concerns of small and medium-sized inventors.
The global landscape for existing utility model rights is a helpful starting point to the discussion on utility model innovation policy at the country-level as well as firm strategy. WIPO data indicates that approximately 3.0 million utility model applications were filed globally in 2022, a growth rate of 2.9% from the previous year and close to the global total of 3.5 million applications for standard patents. Only about one-half of the world’s countries provide for utility model systems, yet companies from around the world acquire these rights. Utility models are important players in the IP environment, and the unique qualities of the system and differential representation require specific analysis. In this chapter, we review existing empirical data and present additional data regarding UM filings and litigation worldwide. Our purpose is to provide background and context for the more detailed discussion in the remaining chapters in this book.
This chapter starts by providing historical perspective on the evolution of the Polish regulatory framework for the protection of utility models. Interestingly, the draft IPL takes us to legislative solutions already tested in the past. One might even say nihil novi sub sole (there is nothing new under the sun). The chapter presents data about the functioning of the regime currently in force. This is followed by a more general discussion, drawing on experience from other jurisdictions, of how various aspects of the regulatory framework might affect the ability of the system to promote innovation. Then, the current legislative framework is presented against the backdrop of the solutions proposed in the draft IPL.
President Trump embraced economic populism centered on trade protectionism, restrictions on international capital and technology flows, and subsidies for American raw material providers and domestic manufacturers. More innovative US counties roundly rejected this economic paradigm: Voters in innovation clusters of all sizes and across the country repudiated Trumpism in both 2016 and 2020. Trump's tariffs and attacks on global supply chains, restrictions on visas for skilled foreign workers, and his overall hostility toward high-tech sectors threatened the innovative firms that motor these places' economies. Trump was different in degree but not kind from previous American populists such as Jennings Bryan and Perot: they too exploited innovation inequality, but were less successful because, before the digital revolution, the industrial organization of American technological progress was not rooted in vertically disintegrated global supply chains. Thus, populism may not only be about resentment toward elites and experts but threaten innovation.
Entrepreneurship has been expunged from contemporary mainstream economics despite being an important driver and cause of economic development and growth. However, whereas Evolutionary Economics recognizes value-creative entrepreneurship, its role and impact tend to still be understated and the vast implications not fully understood. This Element attempts to remedy this by theorizing on how entrepreneurship impacts and drives market economies, the implications for economic change and renewal, and how the pursuit of new value creation determines the evolution of an economy. We find that allowing for entrepreneurial new value creation – innovative entrepreneurship – produces a different and more dynamic understanding of the market as a process, the role of knowledge and uncertainty, economic evolution and progress, as well as has important implications for political economy.
Test educational interventions to increase the quality of care in telemedicine.
Background:
Telemedicine (TM) has become an essential tool to practise medicine around the world. However, education to address clinical skills in TM remains an area of need globally across the health professions. We aim to evaluate the impact of a pilot online learning platform (OLP) and standardized coaching programme on the quality of medical student TM clinical skills.
Methods:
A randomized pilot study was conducted with fourth-year medical students (n = 12). All participants engaged in video-recorded standardized patient (SP) simulated encounters to assess TM clinical skills before and after the intervention. Participants were randomized to either the OLP or OLP + Virtual Coaching Institute (VCI) intervention cohort. Quantitative and qualitative data were collected to address self-reported skills, attitudes, and self-efficacy before the 1st SP encounter and after the 2nd SP encounter. SP encounter recordings were scored by two blinded non-investigator raters based on a standardized rubric to measure the change in TM care delivered pre- and post-intervention. Statistical analysis of quantitative data included descriptive statistics and mixed effects ANOVA.
Findings:
Recruitment and retention of participants exceeded expectations, pointing to significant enthusiasm for this educational opportunity. Self-reported skills and scored simulation skills demonstrated significant improvements for all participants receiving the interventions. Both OLP and VCI interventions were well received, feasible, and demonstrated statistically significant efficacy in improving TM clinical skills. Participants who received coaching described more improvements in self-efficacy, confidence, and overall virtual clinical skills. This study provides evidence that virtualized clinical learning environments can positively impact the development of TM clinical skills among medical students. As TM continues to evolve, the implementation of innovative training approaches will be crucial in preparing the next generation of healthcare professionals for the demands of modern healthcare delivery.
With the recent passage of the Carbon Border Adjustment Mechanism (CBAM), the free allocation of emission permits under the EU Emissions Trading System (EU ETS) that currently acts as a safeguard against emissions leakage and industrial relocation will progressively be phased out. Because the CBAM only covers imports, however, European goods exported into global markets stand to become more vulnerable to emissions leakage. Different policy options have been discussed to counter such export-related leakage, but they variously face concerns regarding their environmental, political, and legal implications. We describe and evaluate the three most important policy options based on their potential to reduce export-related leakage, support the net-zero transformation in Europe as well as globally, ensure conformity with international trade law, secure administrative feasibility, and foster political acceptance by affected trade partners. While no single option outperforms its alternatives on all criteria, our analysis identifies targeted innovation support as a promising option because it minimizes legal and political risks while also offering climate benefits beyond leakage protection for European industry. We then discuss the sectors that are most likely to require innovation support, the policy instruments that could serve to operationalize such support, and potential funding sources. We conclude with guiding principles for technology support measures, reflecting on the implications of the current surge in industrial policy within Europe and beyond.
Work occupies a significant portion of our lives, providing not only financial stability, but also structure, social interaction, and a sense of purpose. In addition, many jobs contribute to society in a beneficial way. While some jobs offer intrinsic satisfaction and personal growth, others may cause stress and burnout. Meaningful work promotes cognitive health by stimulating problem-solving, critical thinking, and learning. Engaging in social interactions at work enhances emotional intelligence and fosters collaboration, creativity, and innovation. Moreover, work contributes to cognitive resilience and may even reduce the risk of dementia in later life. It’s crucial to acknowledge and manage workplace stress through strategies such as maintaining work–life balance, seeking social support, and setting boundaries. This is particularly important considering the increase in hybrid working. Employers play a key role in creating supportive work environments that prioritize employee wellbeing. Overall, meaningful work enriches our lives, promotes cognitive vitality, and contributes to a fulfilling and balanced lifestyle.
Narrative creativity is a new, neuroscience-based approach to innovation, problem solving, and resilience that has proved effective in business executives, scientists, engineers, doctors, and students as young as eight. This Element offers a concise introduction to narrative creativity's theory and practice. It distinguishes narrative creativity from ideation, divergent thinking, design thinking, brainstorming, and other current approaches to cultivating creativity. It traces the biological origins of narrative creativity and explains why narrative creativity will always be mechanically impossible for computer artificial intelligences. It provides practical exercises, developed and tested in hundreds of classrooms and businesses, and validated independently by the US Army, for improving narrative creativity. It explains how narrative creativity contributes to technological innovation, scientific progress, cultural growth, and psychological well-being, and it describes how narrative creativity can be assessed. This title is also available as Open Access on Cambridge Core.