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Introduces and elaborates a distinction between the ‘classic’ and ‘romantic’ perspectives. Contextualises the terms using Goethe’s idea of ‘world literature’. Draws out qualities such as the ‘Olympian detachment’ of the classic perspective and the temporality, self-awareness and will to action of the romantic perspective with right and left political hues. Explores prototypes both in and out of psychiatry and outlines how the perspectives will be used in the book.
Psychiatry is medicine's most multi-disciplinary specialty and arguably its most intellectually and emotionally demanding. It has long attracted dual interpretations from cool, detached perspectives valuing objectivity (classic) to hotter, embodied and more political perspectives valuing subjectivity (romantic). Professor Owen argues that psychiatry should become more aware of classic and romantic threads that run through it. He approaches core topics in psychiatry and throughout the book both research and case material are used to animate the concepts. The author relates psychiatry to questions in philosophical anthropology and ethics. He presents human nature, mental disorder, and human freedom as inherently inter-related. This is a book of broad appeal to anyone interested in psychiatry and why this branch of medicine has ethical, legal and political significance.
Recent changes in US government priorities have serious negative implications for science that will compromise the integrity of mental health research, which focuses on vulnerable populations. Therefore, as editors of mental science journals and custodians of the academic record, we confirm with conviction our collective commitment to communicating the truth.
Restraints are used in various medical settings to control or restrict problematic patient behavior and can be physical, chemical, or environmental. Restraints can produce harmful psychological and physical effects.
Objectives
The prevalence of restraints in geriatric populations in psychiatric hospital settings in the province of Newfoundland and Labrador (NL) has not yet been documented.
Methods
This retrospective cohort study examined whether any form of restraint was used on patients admitted to the Geriatric Psychiatry Unit (GPU) at the Waterford Hospital in St. John’s, NL, from June 1, 2019, to June 1, 2021.
Findings
There were 277 admissions to the GPU during the period of observation, and of these, 189 (68.2%) had a chemical restraint administered, 135 (48.7%) had a physical restraint administered, and 123 patients (44.4%) had both a chemical and physical restraint administered.
Discussion
Restraints are used to control patient behavior for a number of reasons and in a variety of ways. While this practice is used to promote safer environments for patients, it is not without medical, ethical, and political concerns.
This study could promote alternatives to restraints for this geriatric psychiatric population in light of the construction of a new mental health and addictions facility in NL.
Although published over 30 years ago, Motor Disorder in Psychiatry remains a thought-provoking consideration of motor disorder in the context of the psychiatric patients. Rogers hypothesises a common aetiology of motor disorder regardless of a predominating psychiatric or neurological presentation, arguing that the former demands further scrutiny within a neurological/neuropsychiatric framework.
To explore current and potential upcoming legal provisions concerning advance healthcare directives in psychiatry in Ireland, with particular focus on clinical challenges and ethical issues (e.g., self-harm, suicide).
Methods:
Review and analysis of selected relevant sections of the Assisted Decision-Making (Capacity) Act 2015, Assisted Decision-Making (Capacity) (Amendment) Act 2022, Mental Health Act 2001, Mental Health Bill 2024, and Criminal Law (Suicide) Act 1993, and relevant publications from Ireland’s Medical Council and Decision Support Service.
Results:
The Assisted Decision-Making (Capacity) Act 2015 outlined new procedures for advance healthcare directives. The Assisted Decision-Making (Capacity) (Amendment) Act 2022 specified that advance healthcare directives relating to mental health are binding for involuntary patients unless involuntary status is based on Section 3(1)(a) of the Mental Health Act 2001 (i.e., the ‘risk’ criteria). The Mental Health Bill 2024 proposes making advance healthcare directives binding for all involuntary patients. In relation to suicide and self-harm, the Criminal Law (Suicide) Act 1993 states that ‘a person who aids, abets, counsels or procures the suicide of another, or an attempt by another to commit suicide, shall be guilty of an offence’, and the Decision Support Service advises that healthcare professionals are exempted from criminal liability if complying with a valid and applicable advance healthcare directive that refuses life-sustaining treatment, even where the directive-maker has attempted suicide.
Conclusions:
Considerable public and professional education are needed if advance healthcare directives are to be widely used. The ethical dimensions of certain advance directives require additional thought and, ideally, professional ethical guidance.
This chapter provides a brief overview of the endocrine system by describing the different types of hormones and the organs involved in their production. The functions of the main hormones are summarised and the multifaceted relationships between the endocrine system and the nervous systems are discussed. Hormones should not be seen as isolated substances, but as active components of complex pathways with dynamic interactions and signalling mechanisms. A more in-depth understanding of hormonal pathways has led to the emergence of psychoneuroendocrinology, a modern clinical discipline that investigates the reciprocal influences between brain, endocrine system, and psychological processes. Imbalances in hormonal levels can result in pathological changes in both the brain and the body. Specific pathologic responses, such as general adaptation syndrome and allostatic overload, have been described and linked to paradigmatic examples of endocrine imbalances. A neuroendocrinological perspective on psychiatry provides valuable insights about the multiple contributions of hormones to the mechanisms underlying psychopathology.
Neurophysiology is a broad discipline involved in the recording and analysis of biological signals of multiple modalities relevant to the nervous system. Neurophysiological studies have contributed substantially to the understanding of the neurobiological underpinnings of psychiatric disease. In clinical psychiatry, EEG and other studies are secondary to the clinical assessment for a reliable diagnosis and prognostication of psychiatric disease, and should not be interpreted in isolation. However, in some clinical situations, such as non-epileptic seizures, they can be confirmatory of the diagnosis. In this chapter, we start with an overview of basic principles in neurophysiology, from cellular and molecular to systems neuroscience. We then describe the technical aspects, rationale, indications and limitations of the most commonly used neurophysiological tests in clinically psychiatry. We outline the main neurophysiological abnormalities present in primary psychiatric disorders and in their differential diagnoses (delirium, epilepsy, dementia, focal cerebral lesions and sleep disorders), as well as the neurophysiological effect of psychotropic medications. We also describe recent advances in neuromodulation techniques, linking diagnosis to therapy.
Neurology and psychiatry have long been divided as subspecialities of medicine. However, the symptom overlap in central nervous system illness is unmistakable. Medical science has evolved, necessitating a neuropsychiatric approach that is more comprehensive. This editorial briefly outlines the history of neurology and psychiatry and the movement towards a new paradigm.
Major depressive disorder (MDD) is a disabling condition affecting children, adolescents, and adults worldwide. A high proportion of patients do not respond to one or more pharmacological treatments and are said to have treatment-resistant or difficult-to-treat depression. Inadequate response to current treatments could be due to medication nonadherence, inter-individual variability in treatment response, misdiagnosis, diminished confidence in treatment after many trials, or lack of selectivity. Demonstrating an adequate response in the clinical trial setting is also challenging. Patients with depression may experience non-specific treatment effects when receiving placebo in clinical trials, which may contribute to inadequate response. Studies have attempted to reduce the placebo response rates using adaptive designs such as sequential parallel comparison design. Despite some of these innovations in study design, there remains an unmet need to develop more targeted therapeutics, possibly through precision psychiatry-based approaches to reduce the number of treatment failures and improve remission rates. Examples of precision psychiatry approaches include pharmacogenetic testing, neuroimaging, and machine learning. These approaches have identified neural circuit biotypes of MDD that may improve precision if they can be feasibly bridged to real-world clinical practice. Clinical biomarkers that can effectively predict response to treatment based on individual phenotypes are needed. This review examines why current treatment approaches for MDD often fail and discusses potential benefits and challenges of a more targeted approach, and suggested approaches for clinical studies, which may improve remission rates and reduce the risk of relapse, leading to better functioning in patients with depression.
To examine the criteria utilised for detaining individuals under the Irish Mental Health Act 2001 (MHA 2001) and their association with clinical features.
Methods:
Demographic and clinical data of 505 involuntary admissions under the MHA 2001 between 2013 and 2023 were attained. Data included criteria utilised for detention and renewal, sociodemographic and clinical features associated with these criteria, and the use of coercive practices, such as seclusion and restraint.
Results:
The majority of patients who were involuntarily admitted (61.4%), or had their admission order affirmed by tribunal (78.2%), were not judged to pose an immediate risk to themselves or others. Patients admitted under the “impaired judgement criterion” were less likely to be secluded (χ2 = 15.8, p < 0.001) or restrained (χ2 = 11.6, p < 0.01). Patients admitted under the “risk criterion” were younger (KW = 12.7, p = 0.02), and less likely to have a psychotic disorder (χ2 = 5.9, p = <0.001) or have a previous involuntary admission (χ2 = 7.7, p = 0.02). Patients who were subject to coercive care were younger (U = 12739, p < 0.001), more likely to be male (χ2 = 4.6, p = 0.03), and have prolonged involuntary admissions (U = 18412, p = 0.02).
Conclusions:
Currently, the majority of the involuntary care provided for patients under the MHA 2001 is not related to the risk criterion of causing immediate and serious harm to themselves or others, but rather to the criterion of impaired judgement. Patients admitted under the risk criterion are more often subjected to restrictive practices, but are less likely to suffer from psychosis, than those receiving involuntary care due to their impaired judgement.
To set the stage for the US–French case comparison, this chapter shows how the political economy of mental health care was similar in the two countries prior to the Second World War (the critical juncture that initiated deinstitutionalization). One difference, though, stands out: the possibility of coalition formation between workers and managers in public mental health services. On the labor side, French public sector trade unions acquired full legal rights after the war, but the maturation of their US counterparts was late, limited, and staggered across the states. On the management side, the organization of French public psychiatric managers was better equipped to enter into this coalition than its American counterpart. I discuss how these differences came to be. Special attention is paid to the economic interests that drove psychiatrists’ intra-professional conflicts and how their gradual settlement produced diverging organizational outcomes. A discussion of potential confounding factors closes.
Midcentury French policy-makers seemed less committed to expanding public mental health care than their US counterparts, but the psychiatric “sectorization” policy nonetheless took off and ultimately increased the supply of services by the end of the 20th century. This chapter identifies the political factors that produced such results. The presence of a public labor–management coalition in mental health care facilitated three positive supply-side policy feedback cycles, producing the distinctive “French way” of deinstitutionalizing the mentally ill.
Although midcentury US policy-makers showed a robust commitment to expanding public mental health care, services precipitously declined over the following decades. This chapter identifies the political factors that produced such results. The absence of a public labor–management coalition in mental health care facilitated three negative supply-side policy feedback cycles, producing the type of psychiatric deinstitutionalization that has gained international notoriety.
A quirky truth is that the oldest biomarker findings are largely metabolic. These had minimal impact on contemporary thought and research and were largely ignored. They have been rediscovered and validated almost 100 years later, informing our understanding of neurobiology and medical comorbidity and spurring contemporary treatment discovery efforts.
Electroconvulsive therapy (ECT) is a safe and effective treatment for several major psychiatric conditions, including treatment-resistant depression, mania, and schizophrenia; nevertheless, its use remains controversial. Despite its availability in some European countries, ECT is still rarely used in others. This study aims to investigate the experiences and attitudes of early career psychiatrists (ECPs) across Europe towards ECT and to examine how their exposure to ECT influences their perceptions.
Methods
In Europe, a cross-sectional survey was conducted among ECPs, including psychiatric trainees and recently fully qualified psychiatrists.
Results
A total of 573 participants from 30 European countries were included in the study, of whom more than half (N = 312; 54.5%) received ECT training. Overall, ECPs had a positive attitude towards ECT, with the vast majority agreeing or strongly agreeing that ECT is an effective (N = 509; 88.8%) and safe (N = 464; 81.0%) treatment and disagreeing or strongly disagreeing that ECT was used as a form of control or punishment (N = 545; 95.1%). Those who had received ECT training during their psychiatry training were more likely to recommend ECT to their patients (p < 0.001, r = 0.34), and held more positive views on its safety (p < 0.001, r = 0.31) and effectiveness (p < 0.001, r = 0.33). Interest in further education about ECT was moderately high (modal rating on Likert scale: 4, agree), irrespective of prior training exposure.
Conclusions
ECT training is associated with more favorable perceptions of its safety and effectiveness among ECPs. There is a general willingness among ECPs to expand their knowledge and training on ECT, which could enhance patients’ access to this treatment.
Temperature increases in the context of climate change affect numerous mental health outcomes. One such relevant outcome is involuntary admissions as these often relate to severe (life)threatening psychiatric conditions. Due to a shortage of studies into this topic, relationships between mean ambient temperature and involuntary admissions have remained largely elusive.
Aims
To examine associations between involuntary admissions to psychiatric institutions and various meteorological variables.
Methods
Involuntary admissions data from 23 psychiatric institutions in the Netherlands were linked to meteorological data from their respective weather stations. Generalized additive models were used, integrating a restricted maximum likelihood method and thin plate regression splines to preserve generalizability and minimize the risk of overfitting. We thus conducted univariable, seasonally stratified, multivariable, and lagged analyses.
Results
A total of 13,746 involuntary admissions were included over 21,549 days. In univariable and multivariable models, we found significant positive associations with involuntary admissions for ambient temperature and windspeed, with projected increases of up to 0.94% in involuntary admissions per degree Celsius temperature elevation. In the univariable analyses using all data, the strongest associations in terms of significance and explained variance were found for mean ambient temperature (p = 2.5 × 10−6, Variance Explained [r2] = 0.096%) and maximum ambient temperature (p = 8.65 × 10−4, r2 = 0.072%). We did not find evidence that the lagged associations explain the associations for ambient temperature better than the direct associations.
Conclusion
Mean ambient temperature is consistently but weakly associated with involuntary psychiatric admissions. Our findings set the stage for further epidemiological and mechanistic studies into this topic, as well as for modeling studies examining future involuntary psychiatric admissions.