Published online by Cambridge University Press: 21 November 2024
Ménière disease (MD) is a relatively rare disorder of the inner ear classically producing the triad of hearing loss, vertigo, and either tinnitus or a sense of ear fullness with most common onset between 50 and 70 years of age and slight female predominance. Also known as idiopathic endolymphatic hydrops, MD is named after French physician Prosper Ménière after his linking of the condition to the inner ear in 1861. Though the exact pathophysiology remains unclear, MD appears to either be caused by or associated with endolymphatic accumulation in organs of the inner ear, namely, the cochlea, semicircular canals, ampulla, and saccule. Dysfunction is thought to be due to the compensatory dilation of the endolymphatic spaces and caused by unequal endolymph secretion and reabsorption.
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