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Cervico-cephalic arterial dissections (CeAD) are an important cause of stroke in young patients. This study aimed to determine the frequency and predictors of recanalization in spontaneous CeAD and to study the effect of recanalization on functional outcomes.
Methods:
We identified patients presenting with acute ischemic stroke secondary to CeAD from the CT angiography (CTA) database of the Calgary Stroke Program. Dissections were diagnosed based on standard clinical and imaging findings. At the discretion of treating stroke Neurologists, the patients were either treated with single antiplatelet or dual antiplatelet or triple therapy. Follow-up imaging with CTA, magnetic resonance imaging, and DSA was completed, and a Modified Rankin scale (mRS) was performed to determine the outcome.
Results:
Fifty-six patients with CeAdD were studied. Thirty-four patients (18 VAD; vertebral artery dissection and 16 CAD; carotid artery dissection) were followed up for recanalization. Complete recanalization was observed in 27 subjects; 13 patients with VAD recanalized in comparison to 14 with CAD (p = 0.40). All non-recanalized patients had hypertension. A good clinical outcome (mRS ≤ 2) was observed in 47 patients. Interestingly, the likelihood of a good neurological outcome was not influenced by recanalization status. There was no difference in clinical outcome for different sites in VAD, whereas patients with intracranial CAD had severe strokes (NIHSS > 21).
Conclusions:
CeAD has good recanalization rates and neurological outcomes, with recanalization seen even in vessels with initial complete occlusion. The presence of hypertension may influence recanalization. The efficacy of dual antiplatelets and heparin for early recanalization needs to be assessed in future clinical trials.
Migrated ingested foreign bodies in the aerodigestive tract can lodge within vital organs and vessels, causing potentially devastating complications. It is often difficult to localise these foreign bodies, with extrication resulting in the requirement for open approaches which may cause significant morbidity.
Case report
This paper presents the case of an ingested migrated stingray bone lodged adjacent to the vertebral artery in the upper cervical spine. This was managed via an endoscopic transoral approach, with the assistance of an image-guidance system.
Results
Successful extraction of the foreign body was achieved, with minimal residual morbidity.
Conclusion
Our study showed that image-guided endoscopic surgery is a safe, precise and feasible option for the localisation and removal of migrated foreign bodies in the aerodigestive tract involving critical neurovascular structures.
An examination was conducted of the number, level, clinical association and treatment approaches for vertebral arterial loop formation in patients with this condition with and without concurrent cervicogenic dizziness, and classified them according to the vertebral artery segment in which it was present.
Method:
A cross-sectional retrospective study.
Results:
Thirty-seven patients who had undergone double-sided magnetic resonance angiography were examined; vertebral arterial loop formation was observed at only 1 level in 26 patients and at several levels in 9 patients. Segment one (V1) was involved in 78.3 per cent of cases and segment two (V2) was involved in 21.6 per cent. Symptoms in patients with vertebral arterial loop formation included: positional vertigo, in 100 per cent; and pulsatile tinnitus, in 83.7 per cent.
Conclusion:
Loop formation at the vertebral artery was observed most often on the proximal side in patients with cervicogenic dizziness (78.3 per cent). The incidence on the left side was twice as high as on the right side.
We report a case of vertebral artery dissection following direct laryngoscopy, and we provide an update on current knowledge regarding this condition and its relationship to movements of the neck.
Method:
A case report and review of the world literature are presented.
Results:
Vertebral artery dissection is an uncommon event leading to stroke. It has been associated with many risk factors, particularly extreme movement of the cervical spine. The pathogenesis of the condition and the true aetiological significance of neck movement are not known.
Conclusion:
To our knowledge, we present the first case of vertebral artery dissection following direct laryngoscopy. We highlight the need for caution when considering neck pain in patients after direct laryngoscopy.
The term cervico-cephalic arterial dissection (CAD) encompasses a group of arteriopathies not necessarily with an identical pathogenesis but that have in common an intramural hemorrhage. This most frequently affects the extracranial arterial segments, predominantly the internal carotid artery (ICA), the vertebral artery (VA), or multiple arteries in typical locations. Spontaneous cervico-cephalic arterial dissections (sCAD) have typical predilection sites in the different arteries affected, which in part may be explained by mechanical influences: high cervical segment of extracranial ICA or V2 and V3 segments of VA. In the case of a severe head and/or neck trauma, the pathogenesis is straightforward. Magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) have replaced angiography as the gold standard, at least in the extracranial segments of ICA and VA. The risk of having a stroke or transient ischemic attack (TIA) after having suffered a CAD in general is very low.
Although injuries to the vertebral arteries are relatively uncommon, there are several different methods used to gain access to these vessels, and to control any bleeding arising from them. We describe a case of torrential oropharyngeal bleeding following a stab wound to the neck in which rapid access to the vertebral artery was gained using a paramedian mandibulotomy; this approach has not previously been documented. The other approaches are discussed.
Uncontrolled epistaxis may require a long hospital stay, multiple blood transfusions and multiple arterial ligations. Thiscase report highlights vertebro-carotid anastomosis as a rare cause of uncontrolled epistaxis. The importance ofangiography in the identification of rare arterial anastomoses is stressed.
A 10-year-old schoolboy presented with a penetrating wound to the neck after a children's slide accident. A CT scan and endoscopy showed a traumatic oesophageal-cutaneous fistula. Neurologically the child deteriorated over a period of 34 hours and finally succumbed to a respiratory arrest.
Post-mortem findings showed a hypoplastic right vertebral artery. In the left suboccipital triangle a venous clot had blocked the dominant artery thus leading to cerebellar and brainstem infarction.
This extraluminal compression leading to obstruction of an otherwise non traumatized vertebral artery is unique in the literature.
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