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A 53-year-old man developed a left-sided foot drop and a painful sensation on the ventral side of the foot and outer part of the lower leg. Two weeks later, the same symptoms also developed on the right side. In addition, he noticed progressive numbness of his lower legs. Three weeks later, he noticed weakness of his right hand, and was unable to spread his fingers. He had no other symptoms, and his medical history was not informative. He did not recall a tick bite or erythema migrans, or any pulmonary abnormality, and had not visited tropical countries. He does not sit with crossed legs.
Black K-12 students are four times more likely to receive out-of-school suspension than their white peers; housing lenders are more likely to offer black homebuyers subprime loans even when they qualify for prime loans; employers call back candidates for interviews with ‘white-sounding’ names 50 per cent more often than candidates with ‘black-sounding’ names. All these are said to be examples of systemic racism. But what does it mean to say that racism is systemic? Using the tools of social ontology, this article explores the various ways in which social systems can be racist.
The upstream framework presented in public health and medicine considers health problems from a preventive perspective, seeking to understand and address the root causes of poor health. Medical-legal partnerships (MLPs) have demonstrated the value of this upstream framework in the practice of law and engage in upstream lawyering by utilizing systemic advocacy to address root causes of injustices and health inequities. This article explores upstreaming and its use by MLPs in reframing legal practice.
In analyzing the mission of the European Court of Human Rights, it is common to distinguish between what is akin to “individual justice” and what is more akin to “constitutional justice.” The way in which the Court combines the two depends on its “judicial policy.” In this contribution, we will examine how the “systemic” nature of the violations complained of affects the “judicial policy.”
The article looks at how “systemic” irregularities or breaches of law imputable to EU Member States are defined in key legal documents relating to the protection of the EU budget – notably with regards to Agricultural, Structural and Recovery funds, and with regards to the Conditionality Regulation. It is argued that “system deficiencies” arise where the financial interests of the European Union are damaged or put at risk because the systems meant to protect these interests in a Member State are considered deficient themselves. The scope of these systems varies with documents: some systems are defined in sectoral legislation and only have relevance for specific funding programmes; other systems have a more constitutional character and are linked to the protection of the rule of law in EU member states. Moreover, the severity of system deficiencies can be graded on a scale. This has implications regarding the extent of the financial consequences which can be imposed on Member States for the protection of the EU budget – how much EU funding should be withheld from them. It is also argued that the rationales underlying the imposition of financial consequences – putting the EU budget out of harm’s way or incentivizing change to reduce risk? – have implications pertaining to the legal and constitutional relationship established between the EU and its Member States.
Trauma-focused CBT (TF-CBT) is recommended by NICE for adolescents with post-traumatic stress disorder (PTSD). Whilst caregiver involvement is recommended, no specific guidance on the nature of involvement is provided although it is important that involvement takes account of the nature of the trauma. This case report details how Dummett’s systemic CBT formulation was used to plan an intervention such that systemic sessions were included in TF-CBT treatment of an adolescent female with PTSD which arose following interpersonal trauma. Trauma symptoms, trauma cognitions and depressive symptoms were measured throughout, with trauma symptoms showing clinically significant change over the course of therapy. Clinical implications are considered regarding the applicability of systemic CBT formulation and the inclusion of systemic sessions within TF-CBT for adolescents whose traumas arose interpersonally.
Key learning aims
(1) To be able to incorporate systemic factors into a formulation of the maintenance of PTSD for adolescents using Dummett’s systemic cognitive behavioural formulation.
(2) To identify systemic interventions that may facilitate change in interactions between adolescents and parental figures and change in trauma appraisals.
The Athens multifamily therapy project (A- MFTP) provides systemic multifamily group therapy to youths who experienced a first psychotic episode (FEP) and their families.
Objectives
The participants were recruited from the ongoing longitudinal Early Psychosis Intervention Study –ELPIS, Athens FEP Project, which aims to investigate the involvement of genetic and environmental determinants on psychosis risk.
Methods
A group of five families with a child who had experience FEP, attended two multifamily group sessions per month, in the time period from September 2017 to Jun 2018. Parents and offspring participated to the sessions, which were conducted by two co-therapists. Assessment of patients’ psychopathology was based on PANSS at baseline, end of therapy and 6-month follow-up. All participants fulfilled an instrument assessing family factors (SCORE-15) and the Reflective Functioning Questionnaire (RFQ) at the same three time points. Furthermore, participants were asked to give written opinions regarding the therapeutic process at the middle phase, the end of therapy and six months follow - up.
Results
A qualitative analysis identified the emerging themes and patterns, focusing on the language and the meaning constitutes. Communication techniques, emotional processing and problem solving were the main learnings for the members of the group. They highlighted the impact of the group processes on family communication and individual understanding, while the development of a “new family” emerged from the group relationships.
Conclusions
A- MFTP seems to be a promising service aiming to improve mental health and wellbeing of participants, to contrast chronicity and to contribute to early intervention services for psychoses in Greece.
Discrimination has been associated with adverse mental health outcomes, though it is unclear how early in life this association becomes apparent. Implicit emotion regulation, developing during childhood, is a foundational skill tied to a range of outcomes. Implicit emotion regulation has yet to be tested as an associated process for mental illness symptoms that can often emerge during this sensitive developmental period. Youth aged 9–11 were recruited for the Adolescent Brain Cognitive Development (ABCD) study. Associations between psychotic-like experiences, depressive symptoms, and total discrimination (due to race, ethnicity, nationality, weight, or sexual minority status) were tested, as well as associations with implicit emotion regulation measures (emotional updating working memory and inhibitory control). Analyses examined whether associations with symptoms were mediated by implicit emotion regulation. Discrimination related to decreased implicit emotion regulation performance, and increased endorsement of depressive symptoms and psychotic-like experiences. Emotional updating working memory performance partially mediated the association between discrimination and psychotic-like experiences, while emotional inhibitory control did not. Discrimination and implicit emotion regulation could serve as putative transdiagnostic markers of vulnerability. Results support the utility of using multiple units of analysis to improve understanding of complex emerging neurocognitive functions and developmentally sensitive periods.
Mastocytosis is a diverse group of rare diseases due to a clonal proliferation of neoplastic mast cells that can involve a wide variety of organ systems. The two main categories of mastocytosis are cutaneous mastocytosis (CM) showing only skin involvement, and systemic mastocytosis (SM) with at least one extracutaneous organ involved. In many cases of SM, the bone marrow (BM) shows varying degrees of infiltration. Most cases of CM develop during childhood, while adult patients in their fifth and sixth decades tend to present with SM [1]. The clinical course can vary from spontaneous regression in young children with CM to a highly aggressive course primarily seen in adult patients. Even within the category of SM, the presentation can range from indolent to aggressive, and it is thus divided into five subcategories as outlined in the most recent edition of the 2016 World Health Organization (WHO) classification of mastocytosis (Table 12.1) [2]. Of note, mastocytosis is now considered a distinct clinicopathologic entity that is separate from other myeloproliferative neoplasms.
Edited by
Claudia R. Binder, École Polytechnique Fédérale de Lausanne,Romano Wyss, École Polytechnique Fédérale de Lausanne,Emanuele Massaro, École Polytechnique Fédérale de Lausanne
This chapter presents Sustainability Solution Spaces for Decision-Making (SSP) as an integrative method for assessing sustainability. The SSP represents the room to manoeuvre in the system at hand so that it can develop sustainably. The approach fulfils (1) systemic criteria; (2) normative criteria; and (3) procedural criteria. It provides a consistent set of targets and considers the systemic relations among the indicators representing the city-region. This gives the decision-makers concise guidelines for sustainable decisions and makes them aware of the associated trade-offs. SSP can be pursued following a participatory and an expert approach. Whereas the expert approach requires high quality of data, preferably either over time or over a large number of cities, the participatory approach is more flexible and can deal with qualitative data. That is, the expert approach is appropriate for comparing large sets of cities with each other, clustering and providing benchmarks for specific city types, and delivering general indications where policy development is required. The participatory approach might be particularly useful for assessing the impact of a specific project or analysing a specific sector, such as mobility or housing, in depth.
Edited by
Claudia R. Binder, École Polytechnique Fédérale de Lausanne,Romano Wyss, École Polytechnique Fédérale de Lausanne,Emanuele Massaro, École Polytechnique Fédérale de Lausanne
The Integrative Concept of Sustainable Development (ICoS) was developed through an intensive process in order to operationalise the guiding rules of sustainable development in an interdisciplinary team. Through its three general sustainability goals and 25 sustainability rules, ICoS establishes that indicators are part of a step-wise, systematic, and consistent construction that links theoretical abstraction to deliberative action: the political and societal practice of sustainable development (Barton & Kopfmüller, 2012, p. 84). The application of the concept is presented through two examples: a completed project in Santiago de Chile, and a project currently being developed, which will enable the calculation of regional sustainable energy balances.
Edited by
Claudia R. Binder, École Polytechnique Fédérale de Lausanne,Romano Wyss, École Polytechnique Fédérale de Lausanne,Emanuele Massaro, École Polytechnique Fédérale de Lausanne
This chapter presents a comparative analysis of four Participatory Multi-Criteria Approaches (PMCAs) usually applied in sustainability assessments (SMCE, MCM, 3-SPM, and INTEGRAAL). Such approaches are presented in detail and subsequently compared to each other according to three elementary yet crucial questions: who assesses?; what is assessed?; and how is it assessed? The results outline potential synergies and theoretical incompatibilities between the four approaches. The analysis also supports future PMCA applications when choosing one particular approach according to: key meta-principles (i.e., epistemological stance, methodological emphasis); logistical constraints (e.g., time, budget); local idiosyncrasies (e.g., pertinent geographical scales, power asymmetries); and organisational factors.
The STARTTerS Early Childhood Programme at the NSW Service for the Treatment and Rehabilitation of Torture and Trauma Survivors (STARTTS) has been developed in response to the complex refugee experiences of very young children, their families and communities. This biopsychosocial and systemic model is informed by neuroscience, attachment theory and current knowledge of the nature and impact of refugee-specific trauma on very young children and their families. It addresses the complex interactions between, social, cultural and political factors within the trauma and recovery environments, as they influence the clients’ presentations and the choice of interventions with families in cultural transition (FICT).
This paper provides a background to the STARTTerS programme, and reports on the results of a Community Based Participatory Research (CBPR) project with the Karen and Mandaean refugee communities. It explores perceptions and cultural views of signs and symptoms related to early childhood trauma. It also explores help seeking preferences in relation to the recovery, settlement and health needs of families with young children. This research has led to ongoing collaborative and consultative processes with those communities, resulting in the development of services and referral systems, which will build a comprehensive and culturally appropriate early childhood programme.
To evaluate patients with systemic lupus erythematosus and normal hearing over 10 years, compared with healthy controls.
Methods:
Thirty patients diagnosed with systemic lupus erythematosus were evaluated in a prospective, descriptive study. Eight patients fulfilled the inclusion criteria, i.e. normal otoscopy, normal hearing, normal imaging and disease duration of less than one year. Eleven healthy companions of ENT patients were recruited as controls.
Results:
At study commencement, the mean patient age was 32.75 years (range, 15–49 years) and there were no statistically significant audiometric differences between patients and controls. No statistically significant audiometric changes were found either within or between the patient and control groups at 10-year follow up.
Conclusion:
These results supply no evidence for progressive hearing loss in systemic lupus erythematosus patients with no hearing involvement at study commencement. Therefore, we recommend audiometric tests only for systemic lupus erythematosus patients complaining of hearing loss, or for other clinical purposes. It is conceivable that asymptomatic hearing loss could be observed over a more extended follow-up period (i.e. more than 10 years).
Background: Staff working on psychiatric intensive care units (PICUs) are routinely exposed to aggression or threats of aggression from the patients they care for. This phenomenon is identified as an ongoing factor that influences both work performance as well as staff sickness, and as such requires understanding and management.
Aims & method: This study utilized questionnaires assessing the extent to which PICU staff thought violence was a problem and how safe and supported they felt. Semi-structured interviews were conducted with five nurses to gather in-depth information on the factors involved in perceptions of safety and support.
Results: The analysis indicated that as a whole, staff feel safe and supported by their immediate team. Interview analysis produced two main domains and ten sub-domains of experiences that contribute to managing threats, these being grouped in either personal or systemic factors. It particularly highlighted that although patient aggression is a concern, the perception of threat most directly relates to beliefs about a lack of support from other teams and senior management, not the patients themselves.
Conclusions: More research and attention is needed on systemic factors in the management of threatening patients.
Seed treatments are used globally on a wide range of field, vegetable and ornamental seeds, for efficient early season control of insects and diseases. However, specific seed-treatment compounds may be phytotoxic and this phytotoxicity is most acute in laboratory germination tests. Several strategies have been developed to alleviate seed-treatment phytotoxicity that include spatial separation of the pesticide from the seed. This can be accomplished by the application of the active compounds at the end of pelleting or by using a two-pellet system, termed ‘smart-pill technology’. Another approach is to detoxify or adsorb the agrochemical in a standard germination test by applying a peat medium over the seeds in a roll towel or blotter test. Many new seed-treatment chemicals have systemic activity, and the efficacy of these systemic seed treatments depends on the ability of these applied chemical compounds to be absorbed, and then transported in the developing plant. The present article describes seed-coat permeability to systemic seed treatments, examined by monitoring the movement of fluorescent tracers into intact seeds during imbibition. Two moderately lipophilic, fluorescent tracers have been used – rhodamine (ionic) and coumarin (non-ionic) – which differ mainly in electrical charge. Seed-coat permeabilities of particular species have been grouped into three categories: (1) permeable to both tracers; (2) selectively permeable to only coumarin; and (3) non-permeable to both tracers. The ability of a particular compound to diffuse through the seed coat is related to the chemical nature of the seed-covering tissues and the physico-chemical properties of the compound applied.
The treatment of challenging behaviour in intellectual disabilities has evolved dramatically since the 1950s, from a reliance on psychopharmacological restraint and operant conditioning to a multifaceted support plan that recognises the communicative intent of the client alongside their need for meaningful community participation. In recent years there has also been an increasing recognition of the critical role of family relationships in the maintenance and amelioration of challenging behaviour, as well as in attempts to integrate the fields of family therapy and applied behaviour analysis. The aim of this article is to describe a model of tertiary consultation that draws on the skills of systemic family therapy to assist clinicians who might be struggling with responding to challenging behaviour in settings characterised by complex and ‘stuck’ mediation problems. This model applies principles of reflective practice to assist such clinicians to develop a sophisticated understanding of the nature of interactions and relationships in the client's life, a critical prerequisite to the application of behavioural intervention. A detailed description of the model and a case study will be provided.
This article discusses an approach to relational ethics in contemporary systemic practice. It explores the possibilities offered by traditions of moral philosophy in attending to problems from a relational ethics perspective. This includes a focus on relationships as a crucial element in the development and maintenance of a moral self and how couples and families construct an ethical platform together, both consciously and unconsciously; and also how relational ethics may inform ideas about the values-driven problems people present in therapy. Finally, it suggests how ethical responsibility and accountability can be constructed as relational responsiveness. Despite our associations with morality as judgmental and rule driven, moral conduct and decision-making can involve imaginative, creative and aesthetic possibilities.
There is a long history of literature concerning integrative practice and how a systemic practice can fit with other models of therapy. Much of this literature has focused on establishing a space for systemic therapy within the dominant medical paradigm, and exploring how the medical model can be enhanced by systemic ideas. The outcome has been better practice, especially in child and adolescent mental health. Interestingly, however, there has been less discussion of the converse: the family therapy literature has rarely considered whether or not systemic practice itself can be enhanced by ideas from the dominant medical model. This article proposes that a biopsychosocial formulation can enhance systemic practice by: (1) holding clinicians accountable for their thinking; (2) facilitating a rigour and attention to detail that may prove useful when therapy falters; (3) opening up other possibilities for intervention; and (4) providing a way to engage with the dominant medical paradigm and support clients in negotiating their way through this system. Potential problems nevertheless arise when integrating a biopsychosocial formulation into a systemic framework. This article identifies these problems and presents ideas for how they can be managed in practice.