Official Ecuadorian gross domestic product (GDP) data begin in 1950. Prior, only preliminary estimates were available, based on very scattered evidence and broad assumptions. In this paper, we estimate new GDP figures for Ecuador for 1900–50. These are based on the quantitative and qualitative information available for the period, using extensive primary and secondary sources. The new data series allows analysing Ecuador's economic growth and structural change and comparing them to industrialised core countries and other countries in the region. Unlike previous estimates, our series shows a sustained divergence of Ecuador from the core countries during the first half of the 20th century.