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This paper reports an experiment designed to assess the influence of workplace arrangements on the reactions to (the absence of) control. We compare behavior in an Internet and a laboratory principal-agent game where the principal can control the agent by implementing a minimum effort requirement. Then the agent chooses an effort costly to her but beneficial to the principal. Our design captures meaningful differences between working from home and working at the office arrangements. Online subjects enjoy greater anonymity than lab subjects, they interact in a less constrained environment than the laboratory, and there is a larger physically-oriented social distance between them. Control is significantly more effective online than in the laboratory. Positive reactions to the principal’s choice not to control are observed in both treatments, but they are significantly weaker online than in the laboratory. Principals often choose the highest control level, which maximizes their earnings.
When public goods can only be provided when donations cross a minimum threshold, this creates an advantage in that Pareto Efficient outcomes can be Nash Equilibria. Despite this, experiments have shown that groups struggle to coordinate on one of the many efficient equilibria. We apply a mechanism used successfully in continuous public goods games, the Hired Gun Mechanism (Andreoni and Gee in J. Public Econ. 96(11–12):1036–1046, 2012), to see if it can successfully get subjects across the threshold. When we use the mechanism to eliminate only inefficient equilibria, without addressing coordination, there is a modest but statistically insignificant improvement with the mechanism. However, when we hone the mechanism to eliminate all but one of the provision-point equilibria, thereby addressing the coordination issue, the mechanism moves all subjects to the desired efficient outcome almost immediately. In fact, after only one round using the hired gun mechanism, all subject are coordinating on the chosen equilibrium. The mechanism can be applied in settings where a group (1) has a plan for public good provision, (2) can measure contributions, (3) can fine members and (4) has an agreed upon standard for expected contributions. In these settings simple punishments, when focused on solving coordination as well as free riding, can greatly improve efficiency.
This paper contributes to the ongoing methodological debate on context-free versus in-context presentation of experimental tasks. We report an experiment using the paradigm of a bribery experiment. In one condition, the task is presented in a typical bribery context, the other one uses abstract wording. Though the underlying context is heavily loaded with negative ethical preconceptions, we do not find significant differences with our 18 independent observations per treatment. We conjecture that the experimental design transmits the essential features of a bribery situation already with neutral framing, such that the presentation does not add substantially to subjects’ interpretation of the task.
Edited by
James Ip, Great Ormond Street Hospital for Children, London,Grant Stuart, Great Ormond Street Hospital for Children, London,Isabeau Walker, Great Ormond Street Hospital for Children, London,Ian James, Great Ormond Street Hospital for Children, London
The catheterisation laboratory (cath lab) continues to advance with updated technology and novel devices, allowing catheter-based interventions on more complex cases of congenital and acquired heart disease with the added benefit of reduced radiation exposure. Today, a wider range of catheter-based interventions exist, replacing or postponing the need for a surgical approach. Even extremely preterm infants (some less than 800 g) can now be offered interventional procedures in the cardiac catheter laboratory. Conversely, there is a reduced need for cardiac catheterisation as a purely diagnostic tool, as non-invasive imaging modalities such as cardiac CT and MRI continue to increase in their application and sophistication. The anaesthetist will find themselves undertaking high-risk anaesthetics, with challenges inherent to the cath lab, with riskier and more complex children, in a location which may be remote from the theatre suite. Anaesthetists managing children with complex congenital cardiac disease have to understand the pathophysiology of these patients and, importantly, the effects that anaesthesia and any intervention will have on their underlying physiology.
Chapter 3 examines scientific accounts of laboratory experiments and outlines antivivisectionist responses to them. By closely scrutinising physiological texts to reveal the ‘real’ experimenter, antivivisectionists produced a language of textual dissection that became problematically allied with laboratory operations and threatened to undermine the movement’s binary rhetoric of ‘Art vs. Science’. Vivisectors and their opponents shared a rhetoric of intense and absorbing concentration, bodily excision and displacement, and triumphant discovery. The chapter then considers three Victorian novels which creatively adapted the reading strategies advanced by antivivisectionist leaders such as Frances Power Cobbe. Wilkie Collins’s Heart and Science (1883), Edward Berdoe’s St Bernard’s (1887), and Walter Hadwen’s Dr Deguerre (1913–18) proffer supplementary texts including real and fictional pamphlets, newspaper articles, and medical papers. These ancillary materials present alternatives to surgical intervention; they reveal diagnostic information and promote alternative holistic approaches to health which catalyse the fictional vivisector’s demise.
The use of animals as scientific models is argued to be crucial for producing new scientific and medical knowledge and clinical treatments. However, animal research continues to raise socio-ethical concerns. In recent years, there has been a push for openness amongst the life science community, with the aim of increasing the transparency of animal research to wider publics. Yet, how this push for openness is experienced by those responsible for the care and welfare of research animals requires further study. This paper draws upon qualitative interviews with Named Veterinary Surgeons (NVS) in the UK and explores how they practise openness, avoid openness, and, at times, challenge the way their role is represented within openness agendas. Overall, this social scientific analysis reveals that the current openness agenda has the potential to create tensions for professionals, as they seek to manage regulatory and public imaginaries of the veterinary identity alongside the animal research controversy. The paper concludes by arguing for a culture of dialogue, where openness includes allowing those with responsibilities for animal welfare to express ambivalence or concern about their own role. Finally, the paper calls for sustained academic work on relations between the veterinary profession and wider society, particularly areas that involve contested practices in which care and harm may coincide.
This chapter provides guidance on how to send specimens to a virology laboratory, including the need to provide full and accurate patient information, relevant clinical information, how to package and transport specimens and the need to send the correct specimens.
This chapter deals with quality control in the virology laboratory, including quality control and quality assurance. It stresses the need to conduct regular audits of the service to maintain quality standards and the need for accredition schemes (e.g. UKAS). Sources of errors in the laboratory and factors associated with technical quality are also discussed.
This chapter deals with public health and pandemic preparedness. It recognises the five stages of a new pandemic (detection, assessment, treatment, escalation and recovery). The chapter also deals with the issue of laboratory preparedness and the need to maintain a critical mass of laboratory and skilled staff expertise at all times in order to be able to respond rapidly and effectively to a new emerging pandemic.
As in other sciences, an economic experiment is an artificial situation created by a researcher for the purpose of answering one or more scientific questions. Experiments of various types are used in economics to understand the causes of poverty and how it might be alleviated. The methods can identify causal relationships between variables and thereby isolate factors that can lead to poverty as well as to document the behavioral consequences of poverty. Experiments can also be used to provide test beds for proposed policies to alleviate poverty. This essay describes a variety of ways in which experiments have been employed to understand and combat poverty. A line of laboratory experiments that considers which economic institutions are conducive to economic growth is discussed in detail. The results show that decentralized markets are conducive to allowing an economy to operate as efficiently as it can. However, in an economy with a theoretical “poverty trap,” the market works more efficiently if accompanied by a democratic voting process and freedom of communication.
Rats are a well-understood and widely used laboratory species that should be provided with environmentally enriched caging in line with modern animal welfare guidelines. This paper reviews which sources of enrichment are effective and should be prioritised, and how methods for providing enrichment might be selected using rats’ preferences as a guide. Rats demonstrate high demand for social contact and prefer larger cages, and cages with shelters, nesting material and foraging devices. Rats also discriminate between different methods of providing a given type of enrichment. It is clear that rats should be provided with enrichments such as social contact and shelter, and, in fact, that these should probably be considered basic husbandry requirements rather than optional improvements. It is still difficult, however, for animal caretakers to access proven, standardised methods for providing appropriately enriched caging, and the level of enrichment routinely provided to most rats in the laboratory appears to be low. Further research is required to assess the impact of enrichment upon research variables and to develop commercially viable enrichment products for rats in the laboratory.
A study was carried out in Australia and the UK of the legislation and procedures relating to the welfare and use of animals in scientific research. In Australia, a National Code of Practice for the Care and Treatment of Laboratory Animals has been adopted and it is a legal obligation for all Institutions to adhere to the Code. Each institution has an Animal Ethics Committee (AEC) responsible for ethical review and animal welfare which must include, within certain stipulated parameters, a veterinarian, a research scientist, a member of a rights/welfare organisation and an additional lay member. In the UK the situation is different, as the Home Office directly administers the law regarding the use of animals in research. In April 1999 the Ethical Review Process (ERP) was introduced; every Institution must establish an ERP which must include a named veterinarian and representatives from the Animal Care and Welfare Officers and others. In both countries great emphasis is placed on the principles of replacement, reduction and refinement in experimental research. Substantial differences in culture and ethical review structure between the two countries are identified. However, various recommendations are outlined, based on the Australian experience, to build on existing structures and further develop the UK ERP. These recommendations should be seen as long-term aims and seek to further improve animal welfare through facilitating communication, increasing accountability and creating an environment conducive to open discussion.
In this article we examine how a leading Israeli hospital gradually became a large biomedical research facility, resembling a huge laboratory. For Chaim Sheba (1908-1971), the founder and first director of Tel-Hashomer Hospital, the massive immigration to Israel in the 1950s was a unique opportunity for research of diverse human populations, especially Jews who had arrived to Israel from Asia and Africa. The paper focuses on the way research and medical practices were integrated and their boundaries blurred, and studies the conditions under which an entire hospital became a research field. Using the case of one of Israel’s prominent medical institutes, we explore and expand upon the idea of “the hospital as a laboratory,” arguing that, for Sheba, it was not only the hospital but the entire country that functioned as a great research site—a vast laboratory that “had no walls.”
Integrating an appreciation of natural behavior into laboratory studies, and laboratory techniques into field studies allows researchers to examine and control proximate factors while identifying adaptive problems faced by particular species. This focus reveals both important similarities and differences across phylogenetic lineages. Carnivores other than canids have been relatively neglected in the study of cognition. An examination of members of the ursid family reveals the important role of foraging ecology in shaping learning and memory in both wild and captive settings. Whereas top-down approaches tend to be anthropocentric, a bottom-up approach focused on the unique capacities and traits of individual species bears the most fruit in terms of understanding the selective pressures responsible for the emergence and maintenance of those traits.
For millions of people, normal eating is impossible, including persons with chronic bowel disorders, individuals suffering from extensive burns, and patients recovering from major surgery. Not only adults but also newborns and young children are vulnerable. Stanley Dudrick was not the first surgeon to confront this grave reality, but he was the first to devise a highly effective method to feed those who would otherwise succumb from undernourishment. The method is known as Total Parenteral Nutrition. It involves injecting liquid food directly into the bloodstream by a tube connected to a vein, thus bypassing the stomach and small intestine. In the 1960s, medical professionals claimed that feeding a patient entirely by vein was impossible; even if possible, it would be impractical; and even if practical, it would be unaffordable. Through tenacious experimental research, Dudrick proved them wrong, in the process giving life and hope to many who would otherwise have perished.
Since its promotion in 1974, the Heimlich Maneuver has been an invaluable first-aid procedure, which is believed to have saved the lives of countless thousands of choking victims. Henry Heimlich’s life story is one motivated by saving people from unnecessary death and injury. His painstaking development of the abdominal thrust technique is an arresting tale in and of itself. But, so too were his determined efforts to popularize the method in order that ordinary citizens too could become lifesaving heroes. Nevertheless, suffocation by ingestion or inhalation remains the fourth most common cause of preventable death in the United States, requiring that the general public be simply and properly taught on a continuing basis how to administer this vital technique.
Behaviour can be recorded in either the laboratory or the field. In either setting, it can be recorded using standardised behavioural tests that elicit specific behaviour, or by observing freely-behaving subjects. Observation requires decisions about which subjects to observe (sampling rules) and how to record their behaviour (recording rules). There are four sampling rules: ad libitum sampling, focal sampling, scan sampling and behaviour sampling. There are two basic types of recording rule: continuous recording and time sampling; the latter can be further divided into instantaneous sampling and one–zero sampling. Continuous recording is more demanding for the observer but is the only recording method that produces true frequencies and durations. Estimates of frequencies and durations derived from time sampling will be more accurate if the sample interval is short relative to the mean duration of the behaviour. One–zero sampling is likely to yield biased estimates of frequency and duration.
Successful assisted reproduction treatment is critically dependent on consistent laboratory performance. Each laboratory process, from collection of oocytes and preparation of sperm for use in fertilisation in vitro, through embryo culture, assessment, selection for transfer, biopsy for genetic testing, to the storage (cryopreservation) of gametes and embryos for use in later treatment, carries an inherent risk of damage, whether mechanical or through exposure to suboptimal conditions outside the body, with consequences for the chance of successful clinical outcome. Training, competency in specific, unique technical skills and consistent performance of all laboratory practitioners are vital in the ART laboratory. Procedures must be carried out meticulously, adhering to standard operating procedures, with precise attention to detail. Strict adherence to guidelines issued by regulatory and professional bodies is necessary and essential in order to minimise risk and maximise performance. The implementation of a Quality Management System ensures consistent, optimised performance, and facilitates risk assessment and root cause analyses.
The COVID-19 pandemic has had a major impact on clinical practice. Safe standards of practice are essential to protect health care workers while still allowing them to provide good care. The Canadian Society of Clinical Neurophysiologists, the Canadian Association of Electroneurophysiology Technologists, the Association of Electromyography Technologists of Canada, the Board of Registration of Electromyography Technologists of Canada, and the Canadian Board of Registration of Electroencephalograph Technologists have combined to review current published literature about safe practices for neurophysiology laboratories. Herein, we present the results of our review and provide our expert opinion regarding the safe practice of neurophysiology during the COVID-19 pandemic in Canada.