This paper revisits the history of Christianity in the country of ‘Castîliya’, subsequently called the Djerid region located in the southwest of Tunisia, to re-evaluate and add to the large body of documentation that appeared almost a century ago. Excavations carried out by INP researchers in this region located on the limes of Roman Africa have added new data. The information provided either by written sources, notably Christian sources, or by archaeological excavations, suggests that the region of Djerid was Christianized from the fifth century. Indeed, the four main oases (Tusuros, Nepte, Thiges and Aquae) are all bishoprics belonging to the ecclesiastical province of Byzacene and their bishops, converted either to the Donatist or Catholic schism, are almost always present in the provincial gatherings of the church of Africa, usually held in Carthage. Finally, this research tries to answer the following question, what is the fate of the last indigenous Christian communities of Djerid after the Arab-Muslim invasion?