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Dendritic Macromolecules: A Fourth Major Class of Polymer Architecture – New Properties Driven by Architecture

Published online by Cambridge University Press:  10 February 2011

D. A. Tomalia ,
S. Uppuluri ,
D. R. Swanson ,
H. M. Brothers II ,
L. T. Piehler ,
J. Li ,
D. J. Meier ,
G. L. Hagnauer  and
L. Balogh
D. A. Tomalia
Affiliation:
Center for Biologic Nanotechnology, The University of Michigan Medical School, 4027 Kresge II, 200 Zina Pitcher, Ann Arbor, MI 48109–0533 Michigan Molecular Institute, 1910 W. St. Andrews Road, Midland, MI 48640–2696
S. Uppuluri
Affiliation:
Michigan Molecular Institute, 1910 W. St. Andrews Road, Midland, MI 48640–2696
D. R. Swanson
Affiliation:
Michigan Molecular Institute, 1910 W. St. Andrews Road, Midland, MI 48640–2696
H. M. Brothers II
Affiliation:
Michigan Molecular Institute, 1910 W. St. Andrews Road, Midland, MI 48640–2696
L. T. Piehler
Affiliation:
Center for Biologic Nanotechnology, The University of Michigan Medical School, 4027 Kresge II, 200 Zina Pitcher, Ann Arbor, MI 48109–0533
J. Li
Affiliation:
Michigan Molecular Institute, 1910 W. St. Andrews Road, Midland, MI 48640–2696
D. J. Meier
Affiliation:
Michigan Molecular Institute, 1910 W. St. Andrews Road, Midland, MI 48640–2696
G. L. Hagnauer
Affiliation:
Army Research Laboratory, ATTN.: AMSRL-WM-M (Materials Division), Building 4600, Aberdeen Proving Ground, MD 21005–5069
L. Balogh
Affiliation:
Center for Biologic Nanotechnology, The University of Michigan Medical School, 4027 Kresge II, 200 Zina Pitcher, Ann Arbor, MI 48109–0533
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Abstract

This new architectural class of macromolecules has received substantial attention during the past decade. Three dendritic subclasses, which include (a) random hyperbranched (i.e., one-pot ABx, polymerizations), (b) dendritic grafted (i.e., Combburst® polymers) and (c) regular dendrons/dendrimers (e.g., Starburst® dendrimers) have been synthesized and characterized at a well-defined level in our laboratory. It is clear that their precisely controlled, nanoscale dimensions and architecture play critical roles in influencing physical properties and performance characteristics. Furthermore, these parameters have also distinguished dendrimers as fundamental modules for many nanotechnology applications, as well as for the construction of a new class of larger nanoscale entities which we have termed core-shell tecto(dendrimers). This account will overview these activities and focus on certain unique de Gennes dense packing (or congestion phenomena) and nanoscale container properties that have emerged from this novel architecture.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 543: Symposium W – Dynamics in Small Confining Systems IV , 1998 , 289
Copyright
Copyright © Materials Research Society 1999

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