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Concentiration Dependence of the Translational Diffusion of Monoclonal Antibodies Specifically Bound to Phospholipid Langmmuir-Blodgett Films

Published online by Cambridge University Press:  26 February 2011

Lois L. Wright ,
Arthur G. Palmer III  and
Nancy L. Thompson
Lois L. Wright
Affiliation:
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290
Arthur G. Palmer III
Affiliation:
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290
Nancy L. Thompson
Affiliation:
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290
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Extract

The concentration dependence of protein diffusion in solution and in two-dimensional biological membranes is of current theoretical and experimental interest [1]. Langmuir-Blodgett films can be employed to measure protein diffusion coefficients in or on fluid phospholipid bilayers, as a function of protein concentration. Substrate-supported phospholipid monolayers and bilayers have been used extensively as models of immunological cell membranes, and are also of interest in fields other than membrane biophysics, including protein crystallography, medical technology, bioelectronics, optics, and surface science [2,3].

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 110: Symposium M – Biomedical Materials and Devices , 1987 , 419
Copyright
Copyright © Materials Research Society 1988

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References

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