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Delayed contrast MRI for the evaluation of Ménière’s disease: an Australian perspective

Published online by Cambridge University Press:  25 October 2024

Emily Barrett Open the ORCID record for Emily Barrett [Opens in a new window] ,
Rudolf Boeddinghaus ,
Andrew Thompson ,
Andre Wedekind ,
Dayse Tavora-Vieira  and
Jafri Kuthubutheen
Emily Barrett*
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Sir Charles Gairdner Hospital, Nedlands, Australia
Rudolf Boeddinghaus
Affiliation:
Perth Radiological Clinic, Subiaco, Australia Division of Surgery, Medical School, The University of Western Australia, Nedlands, Australia
Andrew Thompson
Affiliation:
Perth Radiological Clinic, Subiaco, Australia Neurological Intervention and Imaging Service of WA (NIISwa), Sir Charles Gairdner Hospital, Nedlands, Australia
Andre Wedekind
Affiliation:
Division of Surgery, Medical School, The University of Western Australia, Nedlands, Australia Department of Audiology, Fiona Stanley Hospital, Perth, Australia
Dayse Tavora-Vieira
Affiliation:
Division of Surgery, Medical School, The University of Western Australia, Nedlands, Australia Department of Audiology, Fiona Stanley Hospital, Perth, Australia School of Population Health, Curtin University, Perth, Australia
Jafri Kuthubutheen
Affiliation:
Division of Surgery, Medical School, The University of Western Australia, Nedlands, Australia Department of Otolaryngology Head and Neck Surgery, Fiona Stanley Hospital, Murdoch, Australia
*
Corresponding author: Emily Barrett; Email: [email protected]
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Abstract

Objectives

Ménière’s disease is a chronic inner-ear disease attributed to endolymphatic hydrops. Magnetic resonance imaging with gadolinium allows visualisation of endolymphatic hydrops in vivo and may be an adjunct to diagnosis.

Methods

Thirty-eight patients suspected of having Ménière’s disease underwent T2 weighted three-dimensional fluid-attenuated inversion recovery and true inversion recovery sequence magnetic resonance imaging 4 hours post double-dose intra-venous gadolinium. Presence of endolymphatic hydrops was graded by two radiologists at 0 and 4 months. Correlation to clinical diagnosis was assessed using Fisher’s exact test.

Results

Hydrops was identified in 88 per cent, 17 per cent and 27 per cent of patients with Definite Ménière’s, Probable Ménière’s and Undifferentiated disease, respectively. A significant correlation existed between diagnosis and presence of hydrops. Sensitivity and specificity were 88 per cent and 67 per cent, respectively. Intra- and inter-observer agreement for presence and grading of hydrops was near-perfect and substantial to near-perfect, respectively.

Conclusion

Magnetic resonance imaging demonstrates radiographic hydrops with significant correlation to clinical diagnosis and good intra- and inter-observer agreement.

Keywords

inner earmagnetic resonance imagerysensorineural hearingtinnitusvertigo
Type
Main Article
Information
The Journal of Laryngology & Otology , First View , pp. 1 - 5
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED.

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Footnotes

Emily Barrett takes responsibility for the integrity of the content of the paper

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