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Accepted manuscript

Sex Differences in Psychosocial Functioning and Neurocognition in Bipolar Disorder: A Systematic Review and Meta-Analysis

Published online by Cambridge University Press:  05 March 2025

Maria Serra-Navarro Open the ORCID record for Maria Serra-Navarro [Opens in a new window] ,
Derek Clougher Open the ORCID record for Derek Clougher [Opens in a new window] ,
Vincenzo Oliva Open the ORCID record for Vincenzo Oliva [Opens in a new window] ,
Clàudia Valenzuela-Pascual Open the ORCID record for Clàudia Valenzuela-Pascual [Opens in a new window] ,
Michele De Prisco Open the ORCID record for Michele De Prisco [Opens in a new window] ,
María Florencia Forte ,
Marina Garriga ,
Brisa Solé Open the ORCID record for Brisa Solé [Opens in a new window] ,
Jose Sánchez-Moreno Open the ORCID record for Jose Sánchez-Moreno [Opens in a new window]  and
Norma Verdolini Open the ORCID record for Norma Verdolini [Opens in a new window]
...Show all authors
Maria Serra-Navarro
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]
Derek Clougher
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB] BIOARABA, Department Psychiatry. Hospital Universitario de Alava. CIBERSAM. University of the Basque Country, Vitoria, Spain
Vincenzo Oliva
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]
Clàudia Valenzuela-Pascual
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]
Michele De Prisco
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]
María Florencia Forte
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]
Marina Garriga
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]
Brisa Solé
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]
Jose Sánchez-Moreno
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB] BIOARABA, Department Psychiatry. Hospital Universitario de Alava. CIBERSAM. University of the Basque Country, Vitoria, Spain
Norma Verdolini
Affiliation:
Local Health Unit Umbria 1, Department of Mental Health, Mental Health Center of Perugia, Perugia, Italy
Giulia Menculini
Affiliation:
Department of Psychiatry, University of Perugia, Perugia, Italy
Alfonso Tortorella
Affiliation:
Department of Psychiatry, University of Perugia, Perugia, Italy
Miquel Bernardo
Affiliation:
Barcelona Clinic Schizophrenia Unit, Hospital Clínic de Barcelona; Departament de Medicina, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]; Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain
J. Antoni Ramos Quiroga
Affiliation:
Department of Mental Health. Hospital Universitari Vall d’Hebron. Barcelona, Catalonia, Spain. Group of Psychiatry, Mental Health and Addictions, Valld’Hebron Research Institute [VHIR]; Vall d’Hebron Research Institute [VHIR]; Barcelona, Catalonia, Spain Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain.
Anabel Martinez-Aran
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]
Eduard Vieta*
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]
Silvia Amoretti
Affiliation:
Department of Mental Health. Hospital Universitari Vall d’Hebron. Barcelona, Catalonia, Spain.
Carla Torrent
Affiliation:
Bipolar and Depressive Disorders Unit, Hospital Clínic de Barcelona; Fundació Clínic-Institut d’Investigacions Biomèdiques August Pi I Sunyer [IDIBAPS]; CIBERSAM, ISCIII, Barcelona, Spain Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències [UBNeuro], Universitat de Barcelona [UB]
*
**Corresponding author: Prof. Eduard Vieta, e-mail: [email protected] Telephone: +34 932275400 ext. 3130, Fax: +34 932279228 Address: Bipolar and Depressive Disorders Unit, Hospital Clinic, University of Barcelona, Institute of Neuroscience, IDIBAPS, CIBERSAM-ISCIII, 170 Villarroel st, 12-0, 08036, Barcelona, Catalonia, Spain

Abstract

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Keywords

sexpsychosocial functioningneurocognitionbipolar disordermeta-analysis
Type
Review/Meta-analysis
Information
European Psychiatry , Accepted manuscript , pp. 1 - 41
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NCCreative Common License - ND
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of European Psychiatric Association

Footnotes

*

The first two authors contributed equally to this work

a

S. Amoretti and C. Torrent should be considered joint last author

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