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A systematic review of the heritability of specific psychopathic traits using Hare’s two-factor model of psychopathy

Published online by Cambridge University Press:  11 May 2017

Sapna Dhanani ,
Veena Kumari ,
Basant K. Puri ,
Ian Treasaden ,
Susan Young  and
Piyal Sen
Sapna Dhanani*
Affiliation:
King’s College London, London, United Kingdom
Veena Kumari
Affiliation:
Institute of Psychiatry, Psychology and Neurosciences, King’s College London, London, United Kingdom
Basant K. Puri
Affiliation:
Hammersmith Hospital and Department of Medicine, Imperial College London, London, United Kingdom
Ian Treasaden
Affiliation:
West London Mental Health NHS Trust and Imperial College Healthcare Trust, London, United Kingdom
Susan Young
Affiliation:
Centre for Mental Health, Imperial College, London, and Broadmoor Hospital, West London Mental Health Trust, London, United Kingdom
Piyal Sen
Affiliation:
Institute of Psychiatry, Psychology, and Neurosciences, King’s College London, and Elysium Healthcare, Chadwick Lodge and Eaglestone View, Hertfordshire, United Kingdom
*
*Address for correspondence: Sapna Dhanani, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology, and Neurosciences, 16 De Crespigny Park, London, SE5 8AF, United Kingdom. (Email: [email protected])
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Abstract

Background

There have been no systematic reviews that investigated the heritability of the two-factor model of psychopathy: interpersonal-affective and behavioral. Our review aimed, first, to examine the heritability of general psychopathic traits and, second, if genetic influences were suggested, to determine the heritability of various traits related to the interpersonal-affective and behavioral factors of psychopathy.

Method

A systematic literature search was conducted using articles from the PsycINFO, Embase, Global Health, Medline, PubMed, Web of Science, and Scopus databases (January of 1980 to December of 2015) in order to identify eligible literature that reported on the heritability of psychopathy-related traits. Papers were also found via manual examination and reference tracking. Papers were subjected to exclusion criteria and quality appraisal. We identified a total of 24 studies.

Results

Our results were grouped into three categories: general, interpersonal-affective, and behavioral. All these areas demonstrated modest to high heritability. The highest heritability values were found in studies investigating callous-unemotional behaviors.

Conclusions

Heritability was found for all the psychopathic traits. Future research should include endophenotypic approaches that explore gene–environment correlations, which could aid in identification of the behavioral phenotype that is most amenable to early intervention by way of moderation of genetic risk.

Keywords

Heritabilitygeneticbehavioralinterpersonal-affectivepsychopathy
Type
Review Articles
Information
CNS Spectrums , Volume 23 , Issue 1 , February 2018 , pp. 29 - 38
Copyright
© Cambridge University Press 2017 

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References

REFERENCES

1. Hare, RD. Psychopaths and their nature: implications for the mental health and criminal justice systems. In: Millon T, Simonsen E, eds. Psychopathy: Antisocial, Criminal, and Violent Behaviour. New York: Guilford Press; 1998: 188–212.Google Scholar
2. Cooke, DJ, Michie, C. Refining the construct of psychopathy: towards a hierarchical model. Psychol Assess. 2001; 13(2): 171. https://pdfs.semanticscholar.org/92ea/84e3e443a8a659b4d279cacb1f9346b4fe0e.pdf. Accessed April 20, 2017.Google Scholar
3. Hare, RD, Hans, V. The Hare Psychopathy Checklist–Revised. North Tonawanda, NY: Multi-Health Systems; 1991. http://www.minddisorders.com/Flu-Inv/Hare-Psychopathy-Checklist.html. Accessed April 20, 2017.Google Scholar
4. Hare, RD, Black, P, Walsh, Z. The PCL–R: forensic applications and limitations. In: Archer RP, Wheeler MA, eds. Forensic Use of Clinical Assessment Instruments, 2nd ed. Mahwah, NJ: Lawrence Erlbaum; 2013: 230–265.Google Scholar
5. Cleckley, HM. The Mask of Sanity: An Attempt to Clarify Some Issues About the So-Called Psychopathic Personality. Bristol, MA: William A. Dolan; 1941.Google Scholar
6. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th ed. Washington, DC: American Psychiatric Publishing; 2013.Google Scholar
7. Crighton, D. Uses and abuses of the Hare Psychopathy Checklist. Evid Based Ment Health. 2009; 12(2): 33–36.CrossRefGoogle ScholarPubMed
8. Skeem, JL, Mulvey, EP, Grisso, T. Applicability of traditional and revised models of psychopathy to the Psychopathy Checklist: screening version. Psychol Assess. 2003; 15(1): 41–55.Google Scholar
9. National Institute for Health and Care Excellence. Antisocial Behaviour and Conduct Disorders in Children and Young People: Recognition, Intervention and Management. NICE Clinical Guidelines, No. 158. London: NICE. https://www.ncbi.nlm.nih.gov/books/NBK299074/. Accessed April 20, 2017.Google Scholar
10. Blonigen, DM, Hicks, BM, Kreuger, RF, Patrick, CJ, Iacono, WG. Psychopathic personality traits: heritability and genetic overlap with internalizing and externalizing psychopathology. Psychol Med. 2005; 35(5): 637–648. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242349/pdf/nihms38985.pdf. Accessed April 20, 2017.CrossRefGoogle ScholarPubMed
11. Neumann, CS, Hare, RD. Psychopathic traits in a large community sample: links to violence, alcohol use, and intelligence. J Consult Clin Psychol. 2008; 76(5): 893–899.CrossRefGoogle Scholar
12. Vandenbroucke, JP, von Elm, E, Altman, DG, et al. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. Ann Intern Med. 2007; 147(8): W163–W194.CrossRefGoogle ScholarPubMed
13. Beaver, KM, Barnes, J, May, JS, Schwartz, JA. Psychopathic personality traits, genetic risk, and gene: environment correlations. Crim Justice Behav. 2011; 38(9): 896–912.CrossRefGoogle Scholar
14. Bezdijan, S, Raine, A, Baker, L, Lynam, D. Psychopathic personality in children: genetic and environmental contributions. Psychol Med. 2011; 41(3): 589–600. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113684/pdf/nihms296482.pdf. Accessed April 20, 2017.Google Scholar
15. Hicks, BM, Carlson, MD, Blonigen, DM, Patrick, CJ, Iacono, WG, Mgue, M. Psychopathic personality traits and environmental contexts: differential correlates, gender differences, and genetic mediation. Personal Disord. 2012; 3(3): 209–227.Google Scholar
16. Reichborn-Kjennerud, T, Ystrom, E, Neale, MC, et al. Structure of genetic and environmental risk factors for symptoms of DSM–IV borderline personality disorder. JAMA Psychiatry. 2013; 70(11): 1206–1214. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927987/. Accessed April 20, 2017.Google Scholar
17. Spatola, CA, Fagnani, C, Pesenti-Gritti, P, Ogliari, A, Stazi, MA, Battaglia, M. A general population twin study of the CBCL/6–18 DSM–oriented scales. J Am Acad Child Adolesc Psychiatry. 2007; 46(5): 619–627.CrossRefGoogle ScholarPubMed
18. Taylor, J, Loney, BR, Bobadilla, L, Iacono, WG, McGue, M. Genetic and environmental influences on psychopathy trait dimensions in a community sample of male twins. J Abnorm Child Psychol. 2003; 31(6): 633–645.Google Scholar
19. Humayun, S, Kahn, RE, Frick, PJ, Viding, E. Callous-unemotional traits and anxiety in a community sample of 7-year-olds. J Clin Child Adolesc Psychol. 2014; 43(1): 36–42.CrossRefGoogle Scholar
20. Lamb, DJ, Middeldorp, CM, van Beijsterveldt, CE, et al. Heritability of anxious-depressive and withdrawn behavior: age-related changes during adolescence. J Am Acad Child Adolesc Psychiatry. 2010; 49(3): 248–255.Google Scholar
21. Viding, E, Blair, RJ, Moffitt, TE, Plomin, R. Evidence for substantial genetic risk for psychopathy in 7-year-olds. J Child Psychol Psychiatry. 2005; 46(6): 592–597.Google Scholar
22. Viding, E, Jones, AP, Frick, PJ, Moffitt, TE, Plomin, R. Heritability of antisocial behaviour at 9: do callous-unemotional traits matter? Dev Sci. 2008; 11(1): 17–22.Google Scholar
23. Anokhin, AP, Golosheykin, S, Grant, J, Heath, AC. Heritability of risk-taking in adolescence: a longitudinal twin study. Twin Res Hum Genet. 2009; 12(4): 366–371.CrossRefGoogle ScholarPubMed
24. Anokhin, AP, Grant, JD, Mulligan, RC, Heath, AC. The genetics of impulsivity: evidence for the heritability of delay discounting. Biol Psychiatry . 2015; 77(10): 887–894. Epub ahead of print Nov 7, 2014. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416979/. Accessed April 20, 2017.CrossRefGoogle ScholarPubMed
25. Burt, SA, Klump, KL. Etiological distinctions between aggressive and non-aggressive antisocial behavior: results from a nuclear twin family model. J Abnorm Child Psychol. 2012; 40(7): 1059–1071. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406250/. Accessed April 20, 2017.Google Scholar
26. Derks, EM, Hudziak, JJ, van Beijsterveldt, CE, Dolan, CV, Boomsma, DI. A study of genetic and environmental influences on maternal and paternal CBCL syndrome scores in a large sample of 3-year-old Dutch twins. Behav Genet. 2004; 34(6): 571–583.Google Scholar
27. Eley, TC, Lichtenstein, P, Moffitt, TE. A longitudinal behavioral genetic analysis of the etiology of aggressive and nonaggressive antisocial behavior. Dev Psychopathol. 2003; 15(02): 383–402.Google Scholar
28. Malone, SM, Vaidyanathan, U, Basu, S, Miller, MB, McGue, M, Iacono, WG. Heritability and molecular-genetic basis of the P3 event-related brain potential: a genome-wide association study. Psychophysiology . 2014; 51(12): 1246–1258. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234198/. Accessed April 20, 2017.CrossRefGoogle ScholarPubMed
29. Tuvblad, C, Raine, A, Zheng, M, Baker, LA. Genetic and environmental stability differs in reactive and proactive aggression. Aggress Behav. 2009; 35(6): 437–452. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771207/. Accessed April 20, 2017.CrossRefGoogle ScholarPubMed
30. Young, SE, Friedman, NP, Miyake, A, et al. Behavioral disinhibition: liability for externalizing spectrum disorders and its genetic and environmental relation to response inhibition across adolescence. J Abnorm Psychol. 2009; 118(1): 117–130. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775710/. Accessed April 20, 2017.Google Scholar