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The incidence and risk factors of fetuses with mirror-image dextrocardia with solitus inversus

Published online by Cambridge University Press:  24 December 2024

Wenjiao Xu Open the ORCID record for Wenjiao Xu [Opens in a new window] ,
Yajuan Wei ,
Xinru Gao ,
Xiaoxue Yang ,
Liping Wang ,
Wenlian Gao ,
Xumin Zhu  and
Baomin Liu Open the ORCID record for Baomin Liu [Opens in a new window]
Wenjiao Xu
Affiliation:
Department of Ultrasound, Xi’an International Medical Center Hospital, Xi’an, Shaanxi, China
Yajuan Wei
Affiliation:
Department of Ultrasound, Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China
Xinru Gao
Affiliation:
Department of Ultrasound, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, China
Xiaoxue Yang
Affiliation:
Department of Ultrasound, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, China
Liping Wang
Affiliation:
Department of Ultrasound, Xi’an International Medical Center Hospital, Xi’an, Shaanxi, China
Wenlian Gao
Affiliation:
Department of Ultrasound, Xi’an Angel Women’s & Children’s Hospital, Xi’an, Shaanxi, China
Xumin Zhu
Affiliation:
Department of Ultrasound, Xi’an Angel Women’s & Children’s Hospital, Xi’an, Shaanxi, China
Baomin Liu*
Affiliation:
Department of Ultrasound, Xi’an International Medical Center Hospital, Xi’an, Shaanxi, China Department of Ultrasound, Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China
*
Corresponding author: Baomin Liu; Email: [email protected]
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Abstract

Objective:

This research seeks to ascertain the prevalence and determinants of mirror-image dextrocardia in fetuses

Study design:

With December 2022 as the reference point, we compiled colleted data on pregnant women who carried fetuses with mirror-image dextrocardia in Xi’an, Shaanxi Province: September–October 2022, November 2022, and December 2022–January 2023. An online questionnaire was distributed to 209 pregnant across China who had contracted COVID-19. The case group comprised women whose final menstrual cycle occurred in November 2022 and who had a fetus with mirror-image dextrocardia. Women with a November 2022 final menstrual period and a fetus without this condition made up the control group. To identify the risk factors associated with fetal mirror-image dextrocardia, both univariate and multivariate logistic regression analyses were employed.

Results:

A significant difference was noted in the gestational age at COVID-19 infection women with a September to October 2022 and December 2022 to January 2023 final menstrual period who did not bear a fetus with mirror-image dextrocardia, and those with a November 2022 final menstrual period whose fetus exhibited this condition. The univariate and multivariate analyses conducted on pregnant women with a final menstrual period in November 2022 who had contracted COVID-19 revealed significant differences in the presence and duration of fever between those bearing fetuses with mirror-image dextrocardia and those without (P = 0.000).

Conclusion:

The findings suggest two critical factors to the increased prevalence of fetal mirror-image dextrocardia: 1) the infection timing which occurs between the 4th and 6th week of pregnancy and 2) the presence of fever and its prolonged duration.

Keywords

Fetal mirror-image dextrocardiaincidence raterisk factors
Type
Original Article
Information
Cardiology in the Young , Volume 35 , Issue 2 , February 2025 , pp. 275 - 282
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Copyright
© The Author(s), 2024. Published by Cambridge University Press

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