Conversation analysts in a range of disciplines have pointed to a relationship between Ethnomethodology and Conversation Analysis. However, full descriptions of key elements of this relationship, and illustrations of how it matters in practical terms, are scarce. We specify ways in which the concerns and sensibility of Ethnomethodology (EM) can translate into the practice of Conversation Analysis (CA). Employing an EM sensibility involves attending to five major features of social interaction: how members of society co-produce social order, achieve social organization in their everyday lives, deploy concrete practices or methods of talk and embodied conduct, use commonsense knowledge, and operate in real-time, actual social interaction with its temporal dimensions. In specifying these features, our aim is to be descriptive, rather than prescriptive. Our goal is to appreciate how EM’s view of social phenomena—as actual, lived in real time, and member-produced—is fundamental to CA, and how EM’s theoretical insights and studies of commonsense and practice-assembled social events profoundly paved the way for CA. While integrating this EM backdrop, CA advanced the systematic analysis of concerted, real-time conduct-in-interaction. A concluding section of the chapter provides an illustration drawn from an internal medicine clinic, and involves doctor-patient interaction.